An autoimmune disease is an overreaction of the immune system against its own cells or organs. Some of these diseases include for example lupus, scleroderma and autoimmune blistering diseases. In autoimmune blistering diseases blistering lesions affect the skin and mucous and membranes. Antibodies mistakenly attack proteins that are substantial for the layers of the skin to stick together. The symptoms and severity of blistering diseases are different from one person to another. In some people, blistering lesions can cover an extensive area of the skin. Although there is not yet a cure for autoimmune blistering diseases, they can often be controlled with treatment.